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Song Wei

Date: Feb-4-2009         Author:          Editor: Admin




Song Wei

Ph.D., MBA
Professor/Director of Beijing Shijitan Hospital Capital Medical University, Laboratory of Oncology.

 

 

 

Translational research in cancer
Cancer biomarkers research and application for diagnosis, therapeutic response and prognosis
Targeted and gene therapy in lung cancer and glioma towards individualized therapy
Mechanisms of action of oncogene and tumor suppressor gene (IGFBP2 and IIp45)

 

[Major Publications (Impact Factor) (Times Cited)]
1. Zhang J, Liu B, Jiang XP, Zhao HZ, Fan M, Fan ZJ, Lee JJ, Jiang T, Jiang TZ, Song SW. A systems biology-based gene expression classifier of glioblastoma predicts survival with solid tumors. PLoS Computational Biology, 2009  (under review). 

2. Wu M, Zhao J, Song SW, Bai H, Wang SH, Yang H, An TT, Wang X, Duan JH, Yuye Wang YY, Zhuo ML, Guo QZ, Liu XY, Liu NH, Wang J. Plasma EGFR mutations are not associated with response to first-line chemotherapy but with prognosis in the Chinese patients with advanced non-small cell lung cancer. Lung Cancer, 2009 (minor revision).

3. Lin Y, Jiang T, Zhou KJ, Xu L, Chen B, Li GL, Qiu XG, Jiang TZ, Zhang W, Song SW. Plasma IGFBP-2 levels predict clinical outcomes of patients with high-grade gliomas. Neuro-Oncology, Jan 27, 2009 (Epub ahead of press). (5.8)

4. Lin Y, Jiang T, Song SW. Plasma IGFBP-2 for prediction of clinical outcomes of patients with gliomas. Journal of Clinical Oncology 26: # 2036, 2008.

5. Mendes KN, Song SW, Fuller GN, Zhang W. IIp45 sensitizes glioma cells to DNA damage-induced cell cycle arrest and apoptosis. Neuro-oncology 8: 399-9, 2006. (5.8)

6. Zhang W, Fuller G, Song SW, Wang G. Regulation of glioma invasion by a pair of interacting and functional opposing proteins IGFBP2 and IIp45. Neuro-Oncology 7: 358-8, 2005. (5.8)

7. Song SW, Zhen Hong, Fuller GN, Zhang W. Inactivation of the invasion inhibitory gene IIp45 by alternative splicing in Gliomas. Cancer Research 65:3562-7, 2005. (7.7) (9)

8. Song SW, Fuller GN , Kong SM, Shen WP, Taylor E, Ramdas L, Zhang W. IIp45, a novel IGFBP-2 binding protein, antagonizes IGFBP-2 stimulation of glioma cell invasion. The Proceedings of National Academy of Sciences 100: 13970-5, 2003. (10.2) (22)

9. Zhang W, Ramdas L, Shen W P, Song SW, Hu L, Hamilton S R. Apoptosis after 5-fluorouracil is mediated by reduced polyamines, non-autocrine Fas ligand, and tumor necrosis factor receptor 2 activation. Cancer Biology & Therapy 2:5, e1-e22, 2003. (3.0) (15)

10. Zhang W, Wang H, Song SW, Fuller G. Insulin-Like growth factor binding protein 2 (IGFBP2): Gene expression microarrays and the hypothesis-generation paradigm. Brain Pathology 12:87-94, 2002. (5.3) (23)

11. Choi W, Song SW, Zhang W. Understanding cancer through proteomics. Technology in cancer research & Treatment 1: 221-30, 2002.

12. Jackson M, Song W, Jin L, Dykes-Hoberg M, Federoff HJ, Sternweis PC, Rothstein JD. Modulation of the neuronal glutamate transporter EAAT4 by two interacting proteins. Nature 410: 89-93, 2001. (29.3) (110).

13. 蒋传路, 魏新亭, Mingang Chen, Song SW, Wei YJ. 大脑胶质瘤概述. In王忠诚 (主审), 江涛 & 刘福生 (主编), 脑胶质瘤, 人民卫生出版社. Beijing. pp. 1-83, 2007.

14. Song SW, Cote G, Wu CL, Zhang W. Alternative splicing: Genetic complexity in cancer. In Zhang W. & Shmulevich, I. (ed.), Computational and Statistical Approaches to Genomics, Kluwer Academic Publishers, Boston, pp, 277-97, 2002.

 

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